Paracetamol (INN) or
acetaminophen (USAN), is a popular analgesic and antipyretic
drug that is used for the relief of fever, headaches, and
other minor aches and pains. It is a major ingredient in
numerous cold and flu medications and many prescription
analgesics. It is remarkably safe in standard doses, but
because of its wide availability, deliberate or accidental
overdoses are not uncommon.
Chemical structure of paracetamol
Paracetamol (Acetaminophen)
Paracetamol, unlike other common analgesics such as aspirin
and ibuprofen, has no anti-inflammatory properties, and so it
is not a member of the class of drugs known as non-steroidal
anti-inflammatory drugs or NSAIDs. In normal doses paracetamol
does not irritate the lining of the stomach nor affect blood
coagulation, the kidneys or the fetal ductus arteriosus (as
NSAIDS can).
Like NSAIDs and unlike opioid analgesics, paracetamol does not
cause euphoria or alter mood in any way. Paracetamol and
NSAIDs have the benefit of being completely free of problems
with addiction, dependence, tolerance and withdrawal.
The words paracetamol and acetaminophen both come from the
chemical names for the compound: N-acetyl-para-aminophenol and
para-acetyl-amino-phenol.
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